为了使人们对基于模型的形变配准在图像引导放疗中的应用状况有个概略了解，在对目前有关基于模型的形变配准方法在图像引导放疗中的应用研究进行调研的基础上，根据形变配准的形变模型和特征空间的选取、相似性度量标准的选取、空间优化等3个主要步骤，以及形变配准方法验证4个方面，对有关基于模型的形变配准方法的文献进行了扼要的分类统计。统计结果表明：目前的形变配准方法在图像引导放疗中的应用研究方向正趋向于在保证形变配准方法的精度与准确度的基础上，通过多分辨率、不同尺度等级、并行计算以及不同优化算法结合等方法来缩短配准时间方面，以满足临床应用的要求。

In order to make people have a broad understanding to the application of medical image deformable registration based on models in image guided radiotherapy, The recent publications that research the application of deformable registration in image guided radiotherapy are concisely classified and summed up according to the three major steps of deformable registration: the selection of deformable model and feature space, the selection of similarity metrics and space optimization, as well as the verification of deformable registrationThe statistics of classification shows that the research directions of deformable image registration which basing to ensure the accuracy and precision of registration, are to combine different kinds of methods, such as multi-resolution, multilevel deformable registration, using parallel computing, and the combination of different kinds of optimization algorithms and so on, in order to shorten the registration time and to meet the clinical demands