本文建立了完整的甲襞流速测量数据模型，指出流速测量必须考虑流向，晃动大小，绝对位移。提出了对甲襞这类目标物有形变及晃动的时间序列配准方法并实现了高精度快速配准，以此补偿晃动和形变，基于配准，通过运动分析首次实现了流速的无原理误差测量。实现结果表明了所提出的方法的有效性。

This paper has built up the mathematical model for velocity measurement of nail fold microcirculation.,It pointed out that three factors should be taken into acdcount, i. e., the flow direction absoluted displacement and wobbling. After presenting the temparal registration method of nailfold microcirculation image series, a fast and accurate registration of nailfold capillaries to compensate the wobbling and deformation is realized. Through motion analysis and based on registration we achieve velocity measurement without principle errors for the first time. The actual measurements verified the effectiveness of our method.